5 edition of Molecular and cellular aspects of erythropoietin and erythropoiesis found in the catalog.
Molecular and cellular aspects of erythropoietin and erythropoiesis
NATO Advanced Research Workshop on Molecular and Cellular Aspects of Erythropoiesis (1986 Bad Windsheim, Germany)
|Statement||edited by Ivan N. Rich.|
|Series||NATO ASI series., vol. 8|
|Contributions||Rich, Ivan N., 1950-, North Atlantic Treaty Organization. Scientific Affairs Division.|
|LC Classifications||QP96 .N38 1986|
|The Physical Object|
|Pagination||viii, 460 :|
|Number of Pages||460|
|LC Control Number||87012726|
Get this from a library! Erythropoietins and erythropoiesis: molecular, cellular, preclinical, and clinical biology. [G Molineux; MaryAnn Foote; S G Elliott;] -- Covers much information on erythropoiesis and red blood cell production, its regulation, and areas of continued research. Discusses topics in the fields of erythropoiesis, recombinant protein. Blut () Blut Â© Springer-Verlag Rich, I.N.: Molecular and cellular aspects of erythropoietin and erythropoiesis. Springer-Verlag, Berlin Heidelberg New York London Tokyo, pages. DM 1 9 8, This book contains the proceedings of a workshop on the "Molecular and Cellular Aspects of Erythropoiesis',' held in The aim of the meeting was to try to discuss and.
"This volume is the result of a workshop entitled Molecular, cellular, and developmental biology of erythropoietin and erythropoiesis, held in Irsee, Germany, on April , , by the New York Academy of Sciences"--Contents page. Description: xiii, pages: illustrations ; 24 cm. Series Title: Annals of the New York Academy of Sciences. PHYSIOLOGY AND PATHOPHYSIOLOGY OF ERYTHROPOIESIS 9 Erythropoietin Regulation in Humans During Exercise and in Extreme Environments 10 Classification and Consequences of Polycythemias (Erythrocytoses) 11 Classification and Consequences of Anemia T Part V. PHARMACOLOGY OF HUMAN ERYTHROPOIETIN AND NOVEL THERAPEUTIC APPROACHES .
the means for producing recombinant erythropoietin for clinical use, molecular cloning of the erythropoietin gene [1—5] has provided a new impetus for studying the biology of erythropoi-etin and the control of erythropoiesis. The use of recombinant erythropoietin . Erythropoietin is the principal hormone that regulates erythropoiesis and its transcription is mediated by hypoxia inducible factor-1 (HIF-1). Binding of Epo to its receptors (EpoR) stimulates erythroid cell division and proliferation and inhibits erythroid progenitor apoptosis Fisher ().
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: Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis (Nato ASI Subseries H:) (): Ivan N. Rich: Books.
Molecular biology has provided a tool with which problems in cellular differentiation can be answered. Recombinant DNA technology has been used to obtain quantities of the erythropoietic hormone, erythropoietin.
The availability of the hormone has provided a much-needed impetus in learning how erythropoiesis is controlled. : Molecular, Cellular, and Developmental Biology of Erythropoietin and Erythropoiesis (Annals of the New York Academy of Sciences) (): New York Academy of Sciences, Rich, Ivan N., Lappin, Terence R.
J.: BooksFormat: Hardcover. Rich, I.N. (): Erythropoietin production by macrophages: Cellular response to physiological oxygen tensions and detection of erythropoietin gene expression by in situ hybridization.
In: Molecular and Cellular Aspects of Erythropoietin and : Ivan N. Rich, Ivan N. Rich. Open Library is an open, editable library catalog, building towards a web page for every book ever published.
Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis by Ivan N. Rich; 1 edition; First published in Erythropoietins and Erythropoiesis: Molecular, Cellular, Preclinical, and Clinical Biology (Milestones in Drug Therapy) [Various.] on *FREE* shipping on qualifying offers.
Erythropoietins and Erythropoiesis: Molecular, Cellular, Preclinical, and Clinical Biology (Milestones in Drug Therapy)Format: Paperback. Erythropoietins, Erythropoietic Factors, and Erythropoiesis: Molecular, Cellular, Preclinical, and Clinical Biology (Milestones in Drug Therapy) 2nd, revised and extended ed.
Edition by Steven G. Elliott (Editor), MaryAnn Foote (Editor), Graham Molineux (Editor) & 0 moreFormat: Hardcover. The cloning of mouse erythropoietin made it possible to develop probes to study the expression of the erythropoietin find the specific mRNA in kidney of stimulated mice and rats, occasionally in liver of stimulated animals but not detectable in spleen, thymus, or salivary glands.
In the study of expression in IW32 cells, that synthesize and secrete erythropoietin constitutively, we found that the. Research on, and interest in, red blood cell formation spans several centuries and was thought to have peaked in the s with the cloning of the eryth- poietin (EPO) gene.
In the years subsequent to the cloning of EPO and its expression as a recombinant protein, much was written about EPO. Molecular and cell biologic aspects of erythropoiesis in long-term bone marrow cultures. Dexter TM, Testa NG, Allen TD, Rutherford T, Scolnick E.
In long-term marrow cultures, proliferation and differentiation of hemopoietic stem cells occurs for several months. Normally, only the most primitive erythroid progenitor cells are produced (the BFU-E).Cited by: Mouse erythroblasts contain approximately 43 Epo receptors per cell with a K d of 90 pM.
The receptor molecule consists of 2 chains, Kd and 66 Kd. The receptor molecule consists of 2 chains, Kd and 66 by: Erythropoietin: From Physiology to conical Trials via molecular biology I. Molecular and Cellular biolgy 2. The molecular Biology of Erythropoietin 3. The STructure-Function Relationship of Erythropoietin 4.
The Regulation of erythropoietin gene expression 5. The biogenesis of erythropoietin in vivo 6. Renal Function and Oxygn Sensing /5(1). Its focus on erythropoiesis represents an attempt to cover a rapidly expanding field, which has gone from elegant studies of erythro poietin physiology, to molecular biology, to clinical applications and again to physiology.
The rapid development has been made possible by cloning of erythropoietin gene and the availability of recombinant : Springer US. NATO Advanced Research Workshop on Molecular and Cellular Aspects of Erythropoiesis ( Bad Windsheim, Germany). Molecular and cellular aspects of erythropoietin and erythropoiesis.
Berlin ; New York: Springer-Verlag, © (OCoLC) Material Type: Conference publication: Document Type: Book: All Authors / Contributors. Get this from a library. Molecular and cellular aspects of erythropoietin and erythropoiesis.
[Ivan N Rich; North Atlantic Treaty Organization. Scientific Affairs Division.;] -- Molecular biology has provided a tool with which problems in cellular differentiation can be answered. Recombinant DNA technology has been used to obtain quantities of the erythropoietic hormone.
Erythropoietins and Erythropoiesis: Molecular, Cellular, Preclinical, and Clinical Biology compiles both pertinent historical and very recent research on this molecule and its clinical utility. The book is divided into two sections: Background and Basic Science and.
The aim of this monograph is to provide an account of the events that led to the transformation of a concept of red cell regulation into an effective treatment of many anemias. Each chapter is authored by investigators who were involved in this transformation and who are still at work on elucidating the origin, kinetics, action, and regulation of this growth hormone.
Clemons G.K. () Some Endocrine Aspects of Renal and Extrarenal Erythropoietin in Normoxic and Hypoxic Rats. In: Rich I.N. (eds) Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis. from book Molecular Basis of Molecular Biology of Erythropoiesis. Erythropoietin is the primary cytokine regulating erythroid cell maturation by signaling through its receptor to activate.
Find many great new & used options and get the best deals for Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis [Nato ASI Su at the best online prices at. The scope of this chapter is to provide a historical overview of the physiology, molecular biology, and gene regulation of erythropoietin.
Commencing with seminal observations of classical medicine linking the blood, oxygen, erythropoiesis, and the kidney, the field progressed into an era of experiments into the whole body physiology, demonstrating the presence of a circulating hormone.The 22 papers provide a broad coverage of the rapid advances in the study of erythropoiesis.
Discusses how heme and its derivatives contribute to the proliferation, differentiation, and maturation of the eurythron, the use of genetic engineering to correct globin gene derangements, various regulators of erythropoiesis as analyzed both in vivo and in vitro, and other topics.Molecular biology of erythropoietin Article Literature Review (PDF Available) in Internal Medicine 43(8) September with Reads How we measure 'reads'.